Human Proteome Project

The Human Proteome Project is a large-scale international initiative which is directed to the identification of all human proteins.

As a result of completion of the Project, cheap and accessible methods of medical diagnostics will be created, the methods being capable to reveal the earliest stages of diseases, providing an individual approach to the treatment of diseases that are considered as incurable at this time.

Roadmap

The Human Proteome Project is focused on the inventory of all human proteins and the revelation of interactions occurring between them. In its scale, this project is superior to the Human Genome Project formally finished in 2001. The basic problems that HPP is facing are: impossibility of detecting single molecules in biological material and a situational nature of a proteome, i.e. the dependence of protein composition on the time and type of tissue and cells. Due to the presence of single amino acid polymorphisms (SAP), alternative splicing (AS) and post-translational modifications (PTM), as part of a whole proteome, one might assume the availability of several million of various protein forms. →

Forum

for disscussing ROADMAP Proteome of the 18th Human Chromosome: Gene Centric Identification of Transcripts, Proteins and Peptides  →